Admittedly, I've not played any of these. The only Trek games I've actually played weren't even really "games" but more simulators--Star Trek Captain's Chair and Star Trek Starship Creator.
Starship Creator was kinda fun to mess around with, but got bogged down too much with the nitty-gritty details and got dull pretty fast, but Captain's Chair was fun to poke around in and explore all the little details and interact with the consoles of all the major starship bridges of its day.