- Lela Dax dies at the age of 114 and the Dax symbiont is joined with Tobin. (DS9: "Equilibrium", "Rejoined")
- Michael Burnham is born on Earth. (DIS: "The Butcher's Knife Cares Not for the Lamb's Cry")
- According to the final draft script of "TOS: "Mudd's Women"", dated 26 May 1966, Montgomery Scott was referred to as being forty years old, indicating that he was born this year. His canon year of birth was later established in TNG: "Relics" as 2222.
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