- USS Enterprise-A encounters Sybok, Spock's half-brother. Sybok hijacks the Enterprise and forces it to travel through the Great Barrier in search of the planet Sha-Ka-Ree and God. They find Sha-Ka-Ree and a very powerful lifeform, but the lifeform is not God. (Star Trek V: The Final Frontier)
- A Federation starship suffers an unexplained ship-wide systems failure for the last time until 2366. (TNG: "Evolution")
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