- Sela is born on Romulus to her mother Tasha Yar after Tasha became the consort of a Romulan general. (TNG: "Redemption II")
- The Albino comes out of hiding, following a narrow escape from Kang, Koloth, Kor, and Curzon Dax on Galdonterre, and establishes a fortified compound on Secarus IV. (DS9: "Blood Oath")
- Kor, while serving on the Klingon Oversight Council, strikes the name Martok off of the Klingon Defense Force's candidate list after noticing that he comes from the lowlands of Ketha Province. Martok later signs on aboard General ShiVang's flagship as a civilian laborer. (DS9: "Once More Unto the Breach")
- In the Delta Quadrant, the Kazon band together and overthrow the Trabe. They steal a large number of Trabe warships, force the Trabe from their homeworld, and head out into space. Soon after this, the Kazon revert to fighting among themselves. (VOY: "Initiations")
- Data graduates from Starfleet Academy and is promoted to ensign. (TNG: "Datalore", "The Measure Of A Man")
- Kurn, brother to Worf, is born on Qo'noS to Mogh and his wife. (TNG: "Sins of the Father")
- Odo assumes humanoid form for the first time. (DS9: "Chimera")
- Michael O'Brien sends a recorded audition of his son Miles playing the cello to the Aldebaran Music Academy. (DS9: "Shadowplay")
- At the age of 17, Miles O'Brien joins Starfleet as an enlisted crewman and is assigned to the USS Rutledge under the command of Benjamin Maxwell. (TNG: "The Wounded"; DS9: "Shadowplay")
- The impending drought on the Crepusculan homeworld was estimated to last until this year. (DIS: "The Vulcan Hello")
- According to the script for "The Storyteller", Hovath was born in this year.
- According to the script for "Melora", Melora Pazlar was born between 2340 and this year. 
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