- Wesley Crusher is born on Earth. (TNG: "Coming of Age", "Family", "True Q")
- Stardate 25102.45: Jack Crusher records a holographic message to his newborn son Wesley. (TNG: "Family")
- Julian Bashir undergoes a DNA resequencing treatment on Adigeon Prime, thereby improving his intelligence and coordination abilities. (DS9: "Doctor Bashir, I Presume")
- The last attempt for reconciliation between Acamar III and the Gatherers prior to 2366 fails. (TNG: "The Vengeance Factor")
- Ensign Data is promoted to lieutenant. (TNG: "Datalore")
- Chakotay graduates from Starfleet Academy. (VOY: "Parallax", "Tattoo", "Endgame")
- Enabran Tain becomes head of the Obsidian Order. (DS9: "In Purgatory's Shadow")
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