Andrea Lopez was a 23rd century Human. She was born on May 23, 2248 at Starbase 2, UFP.
In 2266, she was a Starfleet Academy cadet assigned to a cadet vessel. During an inspection tour of this vessel by Fleet Captain Christopher Pike, there was an accident in engineering in which a baffle plate ruptured. After surviving the initial event, she and four other cadets were rescued by Pike, who was permanently disfigured by the delta radiation. (TOS: "The Menagerie, Part I"; DIS: "Through the Valley of Shadows")
Years earlier in 2257, Pike had a vision of these events on Boreth, which traumatized him so much that a year later he could relive the moment and name the five cadets in a conversation he had with his first officer Una Chin-Riley. Following that conversation, Pike had the computer perform a search for Lopez and the other cadets' names in the United Federation of Planets Citizen Database. (SNW: "Children of the Comet", "A Quality of Mercy")