(written from a Production point of view)
From 1985 through 1987, O'Donnell had a recurring role on the hit television sitcom Night Court in which she played June Wheeler, the wife of future Star Trek: The Next Generation star Brent Spiner's Bob Wheeler. Star Trek III: The Search for Spock actor John Larroquette was a regular on this series; K Callan, Carlos LaCamara, and Kenneth Tobey were among those who appeared in O'Donnell and Spiner's episodes.
O'Donnell has also appeared with other Star Trek alumni on such shows as Highway to Heaven (in an episode with K Callan, John Carr, and Kenneth Tigar), Murder, She Wrote (working alongside Gregg Henry, William Lucking, and Jeff Yagher), Party of Five (with Scott Grimes), Diagnosis Murder (with Sally Kellerman), NYPD Blue (playing a relative of Bill Bolender's character in an episode also featuring Michael Reilly Burke, William Lucking and regulars Gordon Clapp and Sharon Lawrence), Murder One (with Barbara Bosson, John Fleck, Gregory Itzin, and Richard Riehle), Dark Skies (starring Jeri Ryan), The X-Files (with Eve Brenner, Gary Bullock, and Gene Dynarski), The District (with Jonathan Banks and Roger Aaron Brown), and Boomtown (starring Neal McDonough, in an episode with Anthony Montgomery and Vanessa Williams) and Parks and Recreation.
Her feature film credits include Heartbreak Ridge (1986), Baby Boom (1987), Homer and Eddie (1989, starring Whoopi Goldberg), Hot Shots! (1991), Blast from the Past (1999), and The Good Girl (2002). She was also seen in the 1996 HBO science fiction film Menno's Mind, along with Corbin Bernsen, Michael Dorn, Bill Erwin, and Robert Picardo. More recently, O'Donnell starred in The Artist, Transformers: Dark of the Moon and King of California.