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An antivirus or antiviral agent was a drug used to inhibit or abolish microorganisms, specifically viruses.

In 2153, Doctor Phlox developed an antivirus against the mutagenic virus created the Loque'eque which transformed the DNA of other species into their own. (ENT: "Extinction")

The following year, he helped discover an antivirus against the Klingon augment virus. While he initially determined that the virus was a mutated form of the Levodian flu, his partner, Dr. Antaak, had already determined that the new virus was "immune to whatever antiviral we've tried." (ENT: "Affliction") After further study, and with the assistant of Captain Archer, Phlox was able to create and finish an new antivirus, as he was able to use Archer as a host to replicate enough antibodies quicker. (ENT: "Divergence")

Once it was determined that Betazoid Ambassador Lwaxana Troi was affected with Zanthi fever, Dr. Bashir said that a "simple antiviral agent" was all she needed to be cured. (DS9: "Fascination")

In 2377, The Doctor was able to use the hybrid stem cells of the fetal Miral Paris to synthesize an antivirus to cure another Klingon virus, the nehret. (VOY: "Prophecy")

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