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Berthold rays are a form of deadly radiation that causes living animal tissue to disintegrate. There is no known cure or antidote except for the mind-controlling Omicron spores.

The planet Omicron Ceti III is bombared in berthold rays, but unfortunately the rays were not known to Federation science until 2267, after a few colonies had already been established on the planet and wiped out under unknown circumstances. The last colony, the Omicron colony of 2264, was protected by spores until those spores were destroyed by the actions of the USS Enterprise in 2267. The colony had to be relocated because living animal matter could only survive on Omicron Ceti III for a week without protection. (TOS: "This Side of Paradise")

Calamarain probes are known to produce non-lethal broadband emissions, including berthold rays. (TNG: "Deja Q")

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