Beta Penthe was the primary of the Beta Penthe system in Sector 21166, in the Beta Quadrant. This star was orbited by six planets and Rura Penthe, and was located in Klingon territory. The stellar index number for Beta Penthe was 934-83294.

In 2293, the location of Beta Penthe was labeled in the star chart for the "Operation Retrieve" command briefing. The system map, showing the position of the star, was included in the plans for "Operation Retrieve". Both the star chart and map were seen in the office of the Federation President on Earth. (Star Trek VI: The Undiscovered Country set artwork; DIS: "Magic to Make the Sanest Man Go Mad"; PIC: "Maps and Legends")

Rura Penthe, a planetoid located in the Beta Penthe system, was located in the Beta Quadrant on star charts seen in the Star Trek: Discovery episode "Magic to Make the Sanest Man Go Mad" and in the Star Trek: Picard episode "Maps and Legends".
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