Beta Penthe system was a Klingon planetary system in Sector 21166, in the Beta Quadrant. This system consisted of the primary Beta Penthe, six planets, and the planetoid Rura Penthe. Rura Penthe was the location of a penal colony. The stellar index number for Beta Penthe was 934-83294.

In 2293, the location of Beta Penthe was labeled in the star chart for the "Operation Retrieve" command briefing. The system map of Beta Penthe was included in the plans for Operation Retrieve. Both the star chart and map were seen in the office of the Federation President on Earth. (Star Trek VI: The Undiscovered Country set artwork)

In 2399, the location of Beta Penthe was labeled on a star chart that was in Fleet Admiral Kirsten Clancy's office at Starfleet Headquarters. (PIC: "Maps and Legends")

Rura Penthe was located in the Beta Quadrant on a star chart seen in the Star Trek: Discovery episode "Magic to Make the Sanest Man Go Mad".
According to Star Trek: Star Charts (p. 61) and Stellar Cartography: The Starfleet Reference Library ("Stellar Cartography", pp. 27, 30; "Federation Historical Highlights, 2161-2385"), the Beta Penthe system was a binary system with an A-class star and a B-class star. According to a map of the Klingon Empire – prepared by the Scribe K'Tark for the Klingon High Council in the Year of Kahless 893 (2266) – Beta Penthe was identified as a Klingon star.
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