A containment chamber was a device for isolating an object from its surroundings using a solid barrier, in contrast to a containment field, which used an energy barrier.

In 2370, Miles O'Brien set up a containment chamber to hold the protouniverse Jadzia Dax and Arjin brought back from the Gamma Quadrant. (DS9: "Playing God")

In 2373, Captain Kathryn Janeway planned to convert storage bay 3 on the USS Voyager into a containment chamber for sirillium, a highly combustible energy source discovered in a class 17 nebula in the Delta Quadrant. (VOY: "Flashback")