Cuttlefish were marine cephalopods native to the oceans of Earth. They were a source of food for sperm whales, which devoured millions of them as they roamed the oceans.
In 2368, Jean-Luc Picard compared Humans being destroyed in large numbers by the Crystalline Entity to cuttlefish being devoured by sperm whales, suggesting the entity was merely feeding, and had no evil intentions. Kila Marr disagreed, saying they were talking about people, not fish. (TNG: "Silicon Avatar")