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Deep Space 12 was a Federation starbase that was in service with Starfleet in the late 24th century.

In 2399, Jean-Luc Picard had Captain Cristóbal Rios set La Sirena on a course for Deep Space 12 to rendezvous with a Starfleet squadron. At that time, DS12 was the closest Federation starbase to Nepenthe. (PIC: "Broken Pieces")

This starbase was only mentioned in dialogue.
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