In 2152, E'Lis mentioned that their medical supplies went out when the colony's leader Tessic negotiated with Enterprise NX-01 Captain Jonathan Archer about the payment for two-hundred liters of deuterium. She then visited Doctor Phlox in sickbay to choose the medical equipment she needed. Her request for equipment to treat neural shock and a cardiostimulator caused Phlox to suspect that something more than plasma burns had been afflicting the colonists.
It was discovered that Klingon marauders were taking the deuterium and abusing the mining colony for the last five seasons. E'Lis was among those who agreed to fight off the Klingon marauders. (ENT: "Marauders")