In 3069, this class saw the loss of many of its ships to the Burn. Ships with active warp cores were destroyed when their dilithium became inert, resulting in antimatter explosions. (DIS: "People of Earth")
In 3189, the fleet at Federation Headquarters included the USS Nog, a ship of this class. The collective energy of this fleet sustained a distortion field that concealed the headquarters' location. (DIS: "Die Trying")
Dismayed that Cleveland Booker and Ruon Tarka stole the Federation's only prototype of a second generation spore drive in 3190, Fleet Admiral Charles Vance issued orders to scramble all available ships to track them down, including Eisenberg-class ships and shuttles. (DIS: "All In")
- USS Hansando (NCC-325072)
A better view of the design was used in promotional artwork on social media. 
The second edition of Eaglemoss/Hero Collector's Star Trek: Shipyards - Starfleet Ships 2294 to the Future listed both the USS Cuyahoga (NCC-325069) and the USS Grechko (β) (NCC-325071) as members of this class.