Elba II was the inhabited second planet in its star system. The planet had an atmosphere that was poisonous to humanoids and was home to a Federation rehabilitation colony.

Prior to stardate 5718, the Federation took advantage of the inhospitable environment for the establishment of an asylum for the criminally insane – the Elba II asylum, The asylum was administered by a governor. In 2269, the governor was Doctor Donald Cory.

In that year, the Federation starship USS Enterprise delivered a revolutionary new medicine to this asylum. The hope with this medicine was that it would permanently eliminate mental illness. A patient at this asylum, Captain Garth of Izar, a former Starfleet Fleet Captain, was treated with this medicine. (TOS: "Whom Gods Destroy")

In 2328, this planet was home to the Elba II Orbital Transit Station. (TNG-R: "Inheritance")

According to the Star Trek Concordance, "the planet is named after the island of Napoléon I's first exile."
According to the Focus on... Star Trek comic "Captain's Personal Log", this was also the eventual destination of Janice Lester.

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