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Freighter blight was a common medical condition known to afflict Malon personnel on their waste export vessels.

The freighter blight, a form of cell damage, was caused by prolonged exposure to theta radiation. It was fatal unless treated; among its symptoms were blisters and coughing. It could be treated by analeptic compounds.

In 2375, B'Elanna Torres suffered from freighter blight when she had to repair a waste export vessel. (VOY: "Juggernaut")