In the 23rd century, Starfleet starships were capable of performing genetic recombination through an antiproton therapy regimen in a antiproton chamber, though the process could take several hours depending on the extent of the damage.
In 2256, Commander Michael Burnham underwent genetic recombination aboard the USS Shenzhou after being exposed to radiation in the accretion disk of a binary star system for too long. She exited the antiproton chamber before Doctor Nambue could finish the procedure, resulting in the computer to automatically respond that it was a "medical emergency." (DIS: "The Vulcan Hello")
In 3189, Cleveland Booker took his ship into the Verubin Nebula, resulting in a radiation breach that required Dr. Tracy Pollard to use DNA recombination when they got back to the USS Discovery to repair both Booker and Grudge's DNA from the effects. (DIS: "Su'Kal")