Giotto was a 14th century Florentine painter from Earth. Through his creation of the three-point perspective in his art, Giotto was instrumental in the birth of the Renaissance. He saw depth and entirety in his art and, by sharing what he saw with the world, he made a difference by influencing others to look up.
In 3189, upon learning that exploration was a luxury Starfleet could no longer afford, Captain Saru, using the example of Giotto, successfully persuaded Fleet Admiral Charles Vance that the crew of the USS Discovery, with their "unique perspective from a revered time", might help them again to look up. (DIS: "Die Trying")