Glucose (C6H12O6), also known as dextrose, was a simple sugar and carbohydrate that was used as an ubiquitous fuel in most organisms. It served as a source of energy in biological cells. Naturally, it was found in fruits as fructose and in milk as lactose. In humanoid bodies, it was formed in the liver and kidneys by non-carbohydrate intermediates. Glucose was the main product of photosynthesis in plants, aiding in cellular respiration.

In 2256, the sporal therapy used to treat Paul Stametscoma caused an increase in his glucose production. (DIS: "Vaulting Ambition")

Among the symptoms of rop'ngor was fainting, a condition that Worf experienced following his contraction of the disease in 2365. While Worf denied fainting, Doctor Katherine Pulaski went as far as to rephrase herself, describing his condition as a dramatic drop in blood pressure and blood glucose level, leading to circulatory failure, causing unconsciousness. (TNG: "Up The Long Ladder")

Following Tam Elbrun's initial contact with Gomtuu in 2366, his brain activity suggested that he had just come out of some sort of seizure. In addition, his blood pressure and glucose indicated general systemic stress. (TNG: "Tin Man")

In 2367, as Data and Jenna D'Sora were in the process of sitting down for a meal, Data was attempting to explain to her that effects of a low serum glucose level before she interrupted them to discuss their relationship. (TNG: "In Theory")

In 2370, Quark tried to fix a racquetball match between Julian Bashir and Miles O'Brien by attempting to drug the doctor with a "medicinal brew" consisting of water, sucrose, dextrose, tribnel root extract, grain particulates, yeast, synthehol and the anesthetic hyvroxilated quint-ethyl metacetamin. Bashir was unamused. (DS9: "Rivals")

Kathryn Janeway used a glucose bait in 2372 in her attempt to capture a type of burrowing insect to find a cure for the virus she and Chakotay contracted from it while on New Earth. (VOY: "Resolutions")

In 2373, when The Doctor introduced B'Elanna Torres to his family, which was described by her as being a "fantasy" and "ridiculously perfect", she paused the program, explaining that she was "stopping this before [her] blood sugar levels overload." (VOY: "Real Life")

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