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Gregory Calderone (born 10 July 1987; age 37) is an actor who played Lieutenant Jax in the Star Trek: Discovery fifth season episodes "Red Directive" and "Life, Itself".

Calderone appeared in guest roles in episodes of numerous series such as Being Erica, Heartland, Reign (starring Adelaide Kane), Private Eyes (with Nicole de Boer), The Good Doctor (starring Tamlyn Tomita, with Daniel Dae Kim), Frankie Drake Mysteries (with Emmanuel Kabongo and Sara Mitich), and Murdoch Mysteries (with Stephanie Belding).

He played a notable recurring role in the fifth season of Saving Hope (starring Huse Madhavji, with Milton Barnes, Greg Bryk, Thamela Mpumlwana, Kenneth Welsh, Jonathan Whittaker, Raven Dauda, Jonathan Koensgen, and Alex Armbruster). He also had recurring roles in Heroes Reborn (with Hiro Kanagawa, Greg Grunberg, and Nazneen Contractor) and Salvation (starring Santiago Cabrera, with Mark Moses, John Noble, André Dae Kim, Raven Dauda, Brian Markinson, Jeffrey Nordling, Derek Webster, Autumn Reeser, Tara Nicodemo, Andrew Moodie, Sean Connolly Affleck, Simon Northwood, Karen Robinson, and Helene Robbie).

His feature film appearances include This Movie Is Broken (2010, with Stephen McHattie), The Marijuana Conspiracy (2020, with Derek McGrath, Marie Ward, and Morgan Kohan), A Grand Romantic Gesture (2022), and Better Days (2023).

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