High Priestess (in the feminine form) or High Priest (in the masculine form) was a title used by a high ranking spiritual leader. This title was used among Omega IV natives, the Fabrini and Vulcan peoples.
According to the Book of the People, high priestesses were the only Fabrini individuals who could choose their own mates. In 2268, Natira held this position. (TOS: "For the World is Hollow and I Have Touched the Sky")
In 2285, T'Lar held the title of high priestess when she presided at the altar on Mount Selaya and was responsible for performing Spock's fal-tor-pan ritual: the returning his katra from Leonard McCoy. (Star Trek III: The Search for Spock)