This page contains information regarding Star Trek: Short Treks, and thus may contain spoilers.
Iota Geminorum IV was the uninhabited fourth planet in its star system, and the homeworld of the tribble, as well as an abundance of reptiles, the latter keeping the former in check. (ENT: "The Breach")
Around stardate 1421.9, Starfleet scientist Edward Larkin genetically engineered sample specimens of tribbles from the planet. Larkin, who was later described as an idiot, believed them to be a suitable food source save for their very slow breeding rate, which he increased with disastrous consequences. (ST: "The Trouble with Edward")
In 2369, a chart illustrating various creatures, including tribbles, from around the known galaxy was displayed in a classroom aboard Deep Space 9. (TOS: "The Trouble with Tribbles"; DS9: "The Nagus", okudagram)
In order to fulfill their self-given task to hunt the tribble species to extinction, a Klingon armada obliterated the tribbles' homeworld, and by the late 23rd century, the species was entirely eradicated. (DS9: "Trials and Tribble-ations")