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Irritability or crankiness was a type of psychological reaction characterized by annoyance, impatience, and a little bit of anger.

As they played chess in 2265, Spock informed James T. Kirk that on his next move he would checkmate his king. Kirk responded, "Have I ever mentioned you play a very irritating game of chess, Mister Spock?" To which Spock replied, "Irritating? Ah, yes. One of your Earth emotions." At this point, Kirk performed a move which saved his king and then witnessed Spock's facial expression. Kirk asked, "Certain you don't know what irritation is?" (TOS: "Where No Man Has Gone Before")

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