(written from a Production point of view)
Sayre made her television debut in Hercules and the Amazon Women, the 1994 pilot movie for the cult series Hercules: The Legendary Journeys. She was later seen in an episode of Conan and in the 1998 TV movie Legalese. On film, she made her debut with a small role in the 1987 science fiction thriller The Hidden, starring Michael Nouri, William Boyett, and Larry Cedar. This role came after Sayre nearly landed the lead role, that went to Patricia Arquette, in A Nightmare on Elm Street 3. In later years, she has worked only with director Sam Raimi, with small roles in his 1998 thriller A Simple Plan and the blockbusters Spider-Man and Spider-Man 2 (both co-starring Kirsten Dunst).
Besides an occasional on-screen appearance, Sayre also works in the automated dialogue replacement (ADR, or "looping") department for films and TV shows. Among the films for which she has provided her looping services are Something's Gotta Give, The Benchwarmers, For Your Consideration, Shrek Forever After, Oz the Great and Powerful and Grown Ups. She has also supplied voices for TV shows such as 24 and Tru Calling. She is currently starring in a television pilot entitled Star Names Only, directed by Brian Austin Green of Beverly Hills, 90210 fame.