Khan may refer to:
- People
- Khan Noonien Singh, one of the most infamous Augments in Earth's history
- Khan Noonien Singh (alternate reality), his counterpart in the alternate reality
- Genghis Khan, historical dictator of Mongols
- Genghis Khan (Excalbian), a Excalbian recreation of the Mongol leader
- Media
- Star Trek: Khan, a scripted audio series
- Star Trek: Khan (comic series), a comic series set in the alternate reality
- See also
- Kahn, a similar word