The Kiley system was a star system in the Alpha Quadrant. It contained six planets, one of which was Kiley 279, the M-class homeworld of the pre-warp Kiley species. Nearby inhabited star systems included the Talar, Galen, Gamma Trianguli, Alpha Majoris, Scalos, and Algol systems.
The system was located less than a light year from zero point, the location in the Xahea system where Commander Michael Burnham opened a wormhole to the 32nd century at the climax of the battle against Control in 2258.
In 2259, the location of this system was labeled on a stellar cartography chart that was seen on the USS Enterprise's ready room viewscreen. The system's symbol had a white color, indicating its status as a non-aligned system. (SNW: "Strange New Worlds", "Children of the Comet")