Lupo was a Malcorian scientist in the 24th century. In 2367, he worked in the laboratories of the Space Bureau.
When Doctor Mirasta Yale was unexpectedly greeted by Captain Jean-Luc Picard, during a first contact scenario in 2367, Yale's first reaction to his alien appearance was "Is this a joke? Did Lupo and the others from the lab put you up to this?" (TNG: "First Contact")
This character was only mentioned in dialogue.