The Manzar colony was a Federation colony in the Alpha Quadrant. This colony was located in the Manzar system, which was near Sector 441.
Worf visited the colony in 2375 from Deep Space 9 to assist in constructing a new defense perimeter there. Through some unspecified circumstance, this led to his briefly joining the USS Enterprise-E while it was hosting a banquet for the Evora. (Star Trek: Insurrection)
This colony was only mentioned in dialogue.
According to the Star Trek Encyclopedia, 4th ed., vol. 2, p. 17, this colony was located in the same sector as the Evora homeworld.
According to the Star Trek: Star Charts ("United Federation of Planets I", "United Federation of Planets III") and Stellar Cartography: The Starfleet Reference Library ("Federation Historical Highlights, 2161-2385"), the Manzar colony was a Federation member as of 2378.