The matter-antimatter reaction in a Galaxy-class warp core

A matter-antimatter reaction was the reaction of matter and antimatter which resulted in the most exothermal reaction known.

The primary source of power utilized in Federation starships was provided by the enormous amount of output energy produced by a controlled matter-antimatter reaction. This reaction typically occurred within the intermix chamber of a warp core, and was contained by a magnetic containment field. This reaction produced a considerable amount of heat energy in addition to the kinetic energy that was used by the vessel's propulsion system. This heat was supplanted by a plasma coolant system that was situated adjacent to the intermix chamber. The loss of coolant would inevitably result in the overheating and destruction of the intermix chamber, causing a warp core breach. (Star Trek Generations)

Certain types of matter-antimatter reactions were known to create omicron particles. (DS9: "Shadowplay")

The warp core aboard an Intrepid-class starship was fueled by a matter/antimatter reaction, capable of producing a maximum output of 4,000 teradynes per second, providing power for faster-than-light propulsion. (VOY: "Drone") Additionally, the unit of Cochrane was used to measure a matter/antimatter reaction. (VOY: "The Gift")

There was only one ratio with matter-antimatter; 1:1. (TNG: "Coming of Age") However, Lt. Cmdr. Leland T. Lynch once claimed to set a ratio of 25:1. (TNG: "Skin of Evil")

If the antimatter reaction rate, in a matter-antimatter reaction dropped below 9%, it could cause the system's plasma injectors to lock up, which subsequently prevented the nacelles from being initialized. (VOY: "Resistance")

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