Measles was an illness typically contracted by Humans during childhood.

In 2365, after having contracted Rop'ngor and feeling embarrassed, Worf asked Doctor Katherine Pulaski how William T. Riker would feel if he had the measles. She stated that Riker probably would have felt silly as well. (TNG: "Up The Long Ladder")

Adults who contract measles are at actual risk of death from it, and even 24th Century medical advances such as McCoy having isolated immunization agents on Omega IV (which he did in "The Omega Glory") could still be insufficient to remove the risk entirely.

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