The Mekorda sector was a region of space.
In 2370, the USS Enterprise-D searched this sector for potential Federation colony sites, but many of the stars in the sector were main-sequence binary stars without M-class planets, so the search was unsuccessful. The Enterprise also had to endure a magnascopic storm here, which indirectly led to the birth of a new lifeform. (TNG: "Emergence")
According to the script, Mekorda was pronounced as "meh-CORE-da".