In an alternate timeline, Miranda O'Brien was the descendant of Miles O'Brien and Rita Tannenbaum, officers from the Defiant. She lived on the planet Gaia with the rest of the descendants Defiant's crash survivors. When Odo allowed the Defiant to leave Gaia, Miranda was wiped out of existence along with the rest of the descendants. (DS9: "Children of Time")
- Miranda O'Brien was played by actress Jennifer Parsons.