In an alternate timeline, Miranda O'Brien was the descendant of Miles O'Brien and Rita Tannenbaum, officers from the Defiant. She lived on the planet Gaia with the rest of the descendants Defiant's crash survivors.
When Odo changed the flight plan of the Defiant to avoid the crash that would strand the crew and perserve this alternate timeline, Miranda was wiped out of existence along with the rest of the descendants. Odo did this because during the crash Kira would die, and he loved her so much that he refrused to allow this to happen again. (DS9: "Children of Time")
- Miranda O'Brien was played by actress Jennifer Parsons.