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A motor skill was the learned ability to use specific muscles in the body to perform a predetermined outcome of movement. Fine motor skills were a subset in the function of motor skills. Both play a part in motor functions and motor coordination.

Doctor Phlox's study of the Menk in 2151 revealed that there was evidence in his genome study that they are developing increased intelligence, motor skills, linguistic ability, indicating that they were in the process of an evolutionary awakening. (ENT: "Dear Doctor")

In 2370, Juliana Tainer referred to Data's childhood as the time before he recollection of memories. When she elaborated on the idea, she described Data as really be "like a baby, at first" who had difficulties learning how to process sensory information and learning his motor skills. (TNG: "Inheritance")

In Dr. Julian Bashir's review of the medical file on Romulan Chairman Koval in 2375 suggested that he may be in the early stages of Tuvan Syndrome. With such a disease, on average, Koval would start experiencing a loss of motor skills in ten to fifteen years. (DS9: "Inter Arma Enim Silent Leges")

After Tuvok experienced neuroleptic shock, which cause brain damage, his brain quickly began rewiring itself, and among the first functions to return was his basic motor skills. (VOY: "Riddles")

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