NCC-3801 was the registry number of a Federation Ptolemy-class transport/tug that was in service with Starfleet in the mid-23rd century.

At one time the transport container NCC-4000 was attached to NCC-3801. (Star Trek II: The Wrath of Khan; Star Trek III: The Search for Spock)

The registry, like the class, was originally derived from the Star Fleet Technical Manual. According to that manual, NCC-3801 is named the USS Ptolemy and is the prototype of the Ptolemy-class starships.

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