Richard Daystrom having a nervous breakdown.

A nervous breakdown was a term used to describe a sudden attack of mental illness such as depression or anxiety.

In 2268, Doctor Leonard McCoy diagnosed Richard Daystrom with an impending nervous breakdown, if not insanity. (TOS: "The Ultimate Computer")

In 2270, the USS Enterprise's entry into an unidentified energy field placed subatomic particles into their ship's main computer. Once the crew members began to experience practical jokes, Spock identified what the computer was experiencing was the electronic equivalent of a "nervous breakdown." (TAS: "The Practical Joker")

In 2374, Tom Paris left sickbay to check on Harry Kim, who he claimed was having a nervous breakdown following the ensign's complicated interactions with Seven of Nine. (VOY: "Revulsion")

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