Neuromuscular adaptation was a treatment designed to allow species from low-gravity planets to function normally at Earth-normal gravity. The theory was first developed by Nathaniel Teros in 2340, and later refined by Doctor Julian Bashir in 2370.

The procedure utilized neo-analeptic transmitters to elevate the neural output of the brain's motor cortex, which in turn stimulated acetylcholine absorption to 14% above normal and caused an increase in tensile muscle strength. A side effect experienced by the patient during the neo-analeptic infusion was warmth due to neuromuscular tissue stimulation. Eventually, the patient's neural pathways adapted to the increased tensile strength, allowing an increased ability to move in higher gravity.

It was possible for the patient to walk within an hour, although only for an limited period of time as the treatment wore off. With each successive treatment, the effects lasted longer and the patient's muscles grew stronger. It was inadvisable for the patient to alternate between low and Earth-normal gravity conditions during the treatment, as changing stimuli to the motor cortex eventually resulted in the loss of fine motor control.

After two or three days of the treatment, the motor cortex adapted to the new conditions and the effects became irreversible. (DS9: "Melora")

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