Neussite 283 was a highly stable liquid explosive, which was used for industrial infusion charge applications and manufacturing. This explosive was ignited by a microwave pulse detonator. In hypergravity environments, the explosive was to be handled for all applications according to SFRA 3848 precautions. In 2367, this explosive was stored on aboard the Federation starship USS Enterprise-D.
In that year, Neussite 283 was on a list of explosives that Lieutenant Commander Data and Counselor Deanna Troi searched through in an attempt to find one that could produce enough energy to release the USS Enterprise-D and an alien ship from the Tyken's Rift. (TNG: "Night Terrors")