In 2369, there were heightened tensions due to Borg activity. When a Ferengi trading ship entered New Berlin's star system, the colony panicked and sent a distress call. The USS Enterprise-D received the call, but it was quickly cancelled when the ship was identified. The Enterprise acknowledged the colony's signal and transmitted them a copy of the Starfleet ship-recognition protocols, with a suggestion that the colonists read it. (TNG: "Descent")
For the city on Luna, please see New Berlin.