In anatomy, the nose was part of the humanoid face that contained the organs of smell and which marked the beginning of the respiratory tract. The bridge of the nose was supported by two nasal bones. Cetaceans breathed through an organ comparable to the nostril known as a blowhole.
A common symptom of some diseases was a runny nose. (VOY: "Tattoo")
According to Captain Jonathan Archer, the Human astronomer Tycho Brahe lost his nose in a duel over a math equation. (ENT: "The Andorian Incident")
In 2151, Malcolm Reed used a plasma torch as nose for a snowman he and Travis Mayweather built on the surface of Archer's Comet. (ENT: "Breaking the Ice")
While practicing her Denobulan with Doctor Phlox, Hoshi Sato mistakenly used the word for "nostril" instead of "fruit". (ENT: "Dear Doctor")
The holographic character Nicky the Nose was named for his metal nose. (Star Trek: First Contact)
In 2371, B'Elanna Torres broke Joe Carey's nose in three places after an argument in engineering. (VOY: "Parallax")
In 2372, The Doctor described blowing his nose for the first time as an "interesting sensation". (VOY: "Tattoo")
Beetle snuff was consumed via inhalation through the nose. (DS9: "The Nagus")
Worf once developed a gorch on his nose. (Star Trek: Insurrection)
The Doctor was going to have a topic on "Hints for Healthful Living" called "How to keep your nostrils happy". (VOY: "Investigations")