The occipital lobe was the visual processing center of the humanoid brain that contained most of the anatomical region of the visual cortex.

Halanan psychoprojective telepathy caused occipital lobes to give off high amounts of energy. Nidell experienced high levels of energy in her occipital lobe when she projected Fenna in 2370. (DS9: "Second Sight")

In 2373, The Doctor administered hydrocortilene to B'Elanna Torres when she suffered a headache due to an inflammation of her occipital tissues. (VOY: "The Swarm")

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