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Orkett's disease was a virus-caused childhood illness that had swept through Bajoran work camps during the Cardassian Occupation of Bajor. Thousands of children died of it. It might be cured by a bone marrow transplant. The complete Bajoran medical text on the disease was included in the EMH. (VOY: "State of Flux")

In 2371, USS Voyager's EMH discovered that Seska's blood chemistry was not consistent with that of a Bajoran. Her cover story was that she suffered from Orkett's disease as a child during the Occupation of Bajor, and that she had received a bone marrow transplant from a Cardassian woman named Kattell. However, the Doctor had considered and dismissed that explanation before she even brought it up, as it could not sufficiently explain her genetic markers, thus confirming that Seska was Cardassian rather than Bajoran. (VOY: "State of Flux")

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