Orville Wright was an inventor and the brother of Wilbur Wright. Together, the Wright brothers from Ohio were the first to invent aircraft controls that made fixed-wing powered flight possible. (ENT: "North Star")
Their aircraft, the Wright Flyer, was historically significant even as late as the mid 22nd century. On a failed Skagaran colony in the Delphic Expanse, the teacher Bethany educated Human and Skagaran children about the Wright Brothers' historic flight in 2153, showing them a picture of Wilbur, who was flying the plane, and Orville. (ENT: "North Star")
In 2256, trying to motivate Paul Stamets to continue his work on the spore drive, Captain Gabriel Lorca asked if Stamets wanted to be compared to the Wright brothers, Elon Musk, and Zefram Cochrane, or if he wanted to go down in history as a failed scientist. (DIS: "The Butcher's Knife Cares Not for the Lamb's Cry")
In 2372, before Lieutenant Tom Paris attempted the first transwarp flight by Humans, Captain Kathryn Janeway told him he would be joining an elite group of pilots, including Orville Wright. (VOY: "Threshold")
A scene featuring their historic flight is also featured in the opening credits for Star Trek: Enterprise.
Orville Wright was also mentioned in a cut line in the script of Star Trek: First Contact, in which Geordi La Forge refers to the Wright Flyer as "Orville Wright's plane". [1]