This page contains information regarding Star Trek: Discovery, and thus may contain spoilers.
Prior to 3189, following Ryn's attempt to rally the people to rebel against Osyraa, she had his antennae hacked off and sent him to her nephew's salvage yard on Hunhau, where he was forced to implant control devices on the slave laborers, becoming a pariah. (DIS: "Scavengers")
Eventually Osyraa confronted the Discovery while in command of the warship Viridian at the Verubin Nebula. After a brief exchange of dialogue with acting captain Sylvia Tilly, she hijacked the ship once a shockwave, inadvertently caused by Su'Kal almost causing another Burn, knocked out the cloaking devices and shields of both ships. (DIS: "Su'Kal")
Osyraa gained access to Federation Headquarters by piloting Discovery towards Headquarters while the Viridian fired its weapons at it. Discovery was eventually let into Headquarters where Osyraa forced a meeting upon Admiral Charles Vance to discus an alliance between the Chain and the Federation. However, she broke up the talks when Vance said the only way the Federation would accept the alliance was if Osyraa faced justice for her crimes. Osyraa refused and returned to Discovery. However, she discovered that the senior staff, thanks to Ryn disabling the sensors, were attempting to retake control of Discovery. She demanded Ryn to restore the sensors. Ryn refused and Ossyra killed him.(DIS: "There Is A Tide...")
Osyraa attempted to destroy Federation Headquarters. She also had the Viridian open fire on distortion field so Osyraa could escape with Discovery to Base 755. She was unable to use Discovery's spore drive due Burnham's evacuation of Stamets. She was killed by Burnham's phaser during personal combat in Discovery's data core.(DIS: "That Hope Is You, Part 2")