Panama City was a coastal city located in the panhandle of northwest Florida on Earth.

Trip Tucker was born and raised there and attended Bayshore Elementary School there in the early 22nd century, as did one of his former schoolmates, Melissa Lyles. (ENT: "Fusion")

Following the Xindi attack on Earth, Tucker's parents moved from the old home in Panama City to a new house in Mississippi. (ENT: "The Augments")

Amanda Cole's hometown was less than fifty kilometers from Tucker's, making their high schools rivals. (ENT: "Harbinger")

The CGI depiction of the attack on Earth in "The Expanse" contains a serious geographical error. The beam hits Moore Haven, near Lake Okeechobee, in Glades County, south-southeast of Orlando, and cuts a swath directly south to Cuba. Panama City is located in the northern central panhandle roughly seventy miles southwest of Tallahassee, 480 miles north-northwest from the impact point. Panama City could not possibly have been damaged by the attack.

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