(written from a Production point of view)
This is a list of performers who were considered for Star Trek: Deep Space Nine roles, but ultimately did not appear in the role in the final episode or film. Performers listed here have been verified as having been considered by Star Trek personnel for a particular role on Trek in which they ultimately did not appear.
|Performers considered for Star Trek roles|
|The Original Series • Films • The Next Generation • Deep Space Nine • Voyager • Enterprise • Discovery|
- 1 Barbara Alyn Woods
- 2 Richard Dean Anderson
- 3 Teri Austin
- 4 James Avery
- 5 Brigitte Bako
- 6 Kathy Bates
- 7 Richard Beymer
- 8 Lisa Blount
- 9 Jesse Borrego
- 10 Kim Braden
- 11 Suanne Braun
- 12 Claude Brooks
- 13 Pierce Brosnan
- 14 Clancy Brown
- 15 Peter Capaldi
- 16 Bernie Casey
- 17 Kim Cattrall
- 18 Lanei Chapman
- 19 Morris Chestnut
- 20 Claudia Christian
- 21 Doran Clark
- 22 Scott Coffey
- 23 Jeff Conaway
- 24 James Cromwell
- 25 Mary Crosby
- 26 Ben Cross
- 27 Melinda Culea
- 28 Liane Curtis
- 29 Stephen Davies
- 30 Elizabeth Dennehy
- 31 Cliff DeYoung
- 32 Susan Diol
- 33 Tate Donovan
- 34 Michael Dorn
- 35 Maria Doyle
- 36 Marta Dubois
- 37 Kurt Deutsch
- 38 Shelley Duvall
- 39 Samantha Eggar
- 40 Laurence Fishburne
- 41 Michelle Forbes
- 42 John Fleck
- 43 Meg Foster
- 44 Robert Foxworth
- 45 Don Franklin
- 46 John Glover
- 47 Whoopi Goldberg
- 48 Barry Gordon
- 49 Robert Goulet
- 50 Gary Graham
- 51 Faye Grant
- 52 Bruce Greenwood
- 53 Max Grodénchik
- 54 Ronald Guttman
- 55 Martha Hackett
- 56 Molly Hagan
- 57 Charles Hallahan
- 58 Jerry Hardin
- 59 Mariska Hargitay
- 60 Roxanne Hart
- 61 Teri Hatcher
- 62 Jennifer Hetrick
- 63 Leslie Hope
- 64 Jana Marie Hupp
- 65 Famke Janssen
- 66 Salome Jens
- 67 James Earl Jones
- 68 Leilani Jones
- 69 Renée Jones
- 70 Andreas Katsulas
- 71 Jack Kehler
- 72 Brian Krause
- 73 Clyde Kusatsu
- 74 Eriq La Salle
- 75 Ed Lauter
- 76 Sheryl Lee
- 77 Ted Levine
- 78 Kamala Lopez-Dawson
- 79 Charles Lucia
- 80 Franc Luz
- 81 Stephen Macht
- 82 Chase Masterson
- 83 Jeff McCarthy
- 84 Roddy McDowall
- 85 Malcolm McDowell
- 86 Bruce McGill
- 87 Stephen McHattie
- 88 Kate McNeil
- 89 Eric Menyuk
- 90 Tracy Middendorf
- 91 Katherine Moffat
- 92 Cathy Moriarty
- 93 Phil Morris
- 94 Tim Blake Nelson
- 95 Sandra Nelson
- 96 David Newsom
- 97 Julia Nickson
- 98 Natalia Nogulich
- 99 Michael Nunez, Jr.
- 100 Tricia O'Neil
- 101 Terry O'Quinn
- 102 Ed O'Ross
- 103 Corey Parker
- 104 Eric Pierpoint
- 105 Glenn Plummer
- 106 Jon Polito
- 107 Iggy Pop
- 108 James Read
- 109 Richard Riehle
- 110 Charles Rocket
- 111 Andrew Robinson
- 112 Stephen Root
- 113 William Sadler
- 114 Carolyn Seymour
- 115 Martin Sheen
- 116 Gregory Sierra
- 117 Frank Sinatra, Jr.
- 118 Kurtwood Smith
- 119 Rebecca Staab
- 120 Adam Storke
- 121 Brenda Strong
- 122 Cali Timmins
- 123 Hallie Todd
- 124 Tony Todd
- 125 Liz Vassey
- 126 John Vickery
- 127 Chuck Wagner
- 128 Robert Walker
- 129 Basil Wallace
- 130 Dylan Walsh
- 131 Gwynyth Walsh
- 132 Sydney Walsh
- 133 David Warner
- 134 Carl Weathers
- 135 Edward Wiley
- 136 Barbara Williams
- 137 Fred Williamson
- 138 Ray Wise
- 139 Tom Wright
Barbara Alyn Woods
- Main article: Barbara Alyn Woods
Barbara Alyn Woods (born 11 March 1962; age 58) was considered and auditioned for the role of both Kira Nerys and Jadzia Dax.   Alyn Woods had previously appeared as Kareen Brianon in TNG: "The Schizoid Man".
Richard Dean Anderson
Richard Dean Anderson (born 23 January 1950; age 70) was reportedly considered for the role of Commander Benjamin Sisko. (Science Fiction Television Series, 1990-2004: Histories, Casts and Credits for 58 Shows, p. 266)
Anderson came to the spotlight for his role of the title character in the television series MacGyver from 1985 to 1992. He later took the role of Jack O'Neill in the television series Stargate SG-1 from 1997 through 2007, Stargate Atlantis from 2004 to 2007 and Stargate Universe from 2009-2010.
Austin is best known for her role as Jill Bennett in the soap opera Knots Landing between 1985 and 1989. She has also appeared in such series as Quantum Leap (starring Scott Bakula and Dean Stockwell), Wings, Murder, She Wrote (starring William Windom) and Models, Inc..
- Main article: James Avery
James Avery (27 November 1945 – 31 December 2013; age 68) was considered for the role of Benjamin Sisko, however, he was not available due to co-starring in the sitcom The Fresh Prince of Bel-Air at the time.  Avery later appeared as General K'Vagh in ENT: "Affliction" and "Divergence".
Bako is a Canadian actress, best known for her roles in such series as Red Shoe Diaries and Californication, and such films as Strange Days (1995). She also lent her voice to such animated shows like Godzilla: The Series and Gargoyles.
- Main article: Richard Beymer
Richard Beymer (born 20 February 1938; age 82) was considered for the role of Benjamin Sisko, however, he was busy directing a film at the time.  Later, Beymer played Li Nalas in the second season episodes "The Homecoming", "The Circle", and "The Siege".
Blount has appeared in films such as An Officer and a Gentleman (1982), Cease Fire (1985), and Blind Fury (1989), and series such as Murder, She Wrote (starring William Windom), Picket Fences, and Judging Amy.
- Main article: Kim Braden
Kim Braden (born November 1949; age 71) was considered and auditioned for the role of Kira Nerys.  Braden is the wife of "Emissary" director David Carson. She had previously appeared as Ensign Janet Brooks in TNG: "The Loss", and went on to play Elise Picard in Star Trek Generations, directed by Carson.
Suanne Braun (born 29 February 1968; age 52) auditioned and was initially accepted for the role of Arandis. However, by the time she arrived for her costume fitting, she was informed that Vanessa Williams had expressed interest in the role the night before and had been subsequently cast. 
Immediately following, Braun would go on to audition and be accepted for the role of Hathor in Stargate SG1.
Brosnan is most famous for the television series Remington Steele and for playing James Bond in four films, including GoldenEye (1995) with Famke Janssen, and Tomorrow Never Dies (1997) with Teri Hatcher, Michelle Yeoh, and Vincent Schiavelli.
- Main article: Clancy Brown
Clancy Brown (born 5 January 1959; age 62) was considered for the role of Benjamin Sisko, however, he was not available due to back surgery at the time.  A decade later, Brown appeared as Zobral in ENT: "Desert Crossing".
Capaldi is a British actor, most famous for playing the Twelfth Doctor in the British science fiction series Doctor Who from 2013 to 2017. He also played spin doctor Malcom Tucker in the sitcom The Thick of It from 2005 to 2012. He also appeared in films such as Bean (1997, with Harris Yulin, Danny Goldring and Larry Drake), Max (2002), In the Loop (2009), and The Fifth Estate (2013, with Benedict Cumberbatch and Alexander Siddig).
- Main article: Bernie Casey
Bernie Casey (8 June 1939 – 19 September 2017; age 78) was considered and auditioned for the role of Benjamin Sisko. (Science Fiction Television Series, 1990-2004: Histories, Casts and Credits for 58 Shows, p.266) He later appeared as Calvin Hudson in two episodes of DS9.
- See: Kim Cattrall
- Main article: Lanei Chapman
Lanei Chapman (born 23 January 1973; age 47) was considered and auditioned for the role of Jadzia Dax.  Chapman had previously appeared as Ensign Sariel Rager in TNG: "Galaxy's Child", "Night Terrors", "Relics", and "Schisms".
- See: Claudia Christian
Clark has appeared in several series in guest roles, such as MacGyver, Murder, She Wrote (starring William Windom), Quantum Leap (starring Scott Bakula and Dean Stockwell), and Chicago Hope (starring Jayne Brook).
Jeff Conaway (5 October 1950 – 27 May 2011; age 60) was reportedly approached for an unspecified guest role on either Star Trek: Deep Space Nine or Star Trek: Voyager, but declined. Conaway mentions the offer in the DVD audio commentary for the Babylon 5 TV movie Thirdspace. Conaway was a series regular as Security Chief Zack Allan on the Babylon 5 series, along with Andreas Katsulas, Bill Mumy, Patricia Tallman, Robert Rusler, and Tracy Scoggins. He also reprised the role in the aforementioned Thirdspace (which co-starred Clyde Kusatsu), River of Souls (with Joel Brooks), and A Call to Arms (with Tony Todd). Conaway is best known for his role as Kenicke in the 1978 film adaptation of the musical Grease and as taxi-driver/struggling actor Bobby Wheeler on the sitcom Taxi (with Christopher Lloyd).
- Main article: James Cromwell
James Cromwell (born 27 January 1940; age 80) was considered and auditioned for the role of Odo.  Cromwell had previously appeared as Prime minister Nayrok in TNG: "The Hunted". He went on to play Jaglom Shrek in TNG: "Birthright, Part I" and "Birthright, Part II", Minister Hanok in DS9: "Starship Down", and Zefram Cochrane in Star Trek: First Contact and ENT: "Broken Bow".
- Main article: Mary Crosby
- Main article: Ben Cross
- Main article: Melinda Culea
Curtis started her career as a child actress at the age of 4, and subsequently appeared in films such as Sixteen Candles (1983), The Brother from Another Planet (1984), and Benny & Joon (1993), and series such as Married... with Children and ER.
- Main article: Stephen Davies
Stephen Davies was considered and auditioned for the role of Benjamin Sisko.  Davies went on to play the Saratoga Tactical officer in "Emissary", Arak'Taral in "Hippocratic Oath", and Nakahn in VOY: "Darkling".
- Main article: Elizabeth Dennehy
Elizabeth Dennehy (born 1 October 1960; age 60) was considered and auditioned for the role of Kira Nerys.  Dennehy had previously appeared as Commander Shelby in TNG: "The Best of Both Worlds" and "The Best of Both Worlds, Part II".
- Main article: Cliff DeYoung
- See: Susan Diol
- Main article: Michael Dorn
Michael Dorn (born 9 December 1952; age 68) was to appear as the mirror universe counterpart of his Next Generation character, Worf in "Crossover". The schedule conflicted with the filming of TNG. 
Maria Doyle Kennedy (born 25 September 1964; age 56) in an Irish singer and actress, who was considered for the role of Kira Nerys, but she was not available due to music commitments at the time. 
Doyle is best known for her television roles in such series as Father Ted (1998), The Tudors (2007-10), Downtown Abbey (2011), and Orphan Black (2013-17).
- Main article: Marta Dubois
- Main article: Samantha Eggar
Fishburne is most famous for playing Morpheus in The Matrix (1999) and its two sequels and Doctor Raymond Langston in three seasons of CSI: Crime Scene Investigation (co-starring Wallace Langham and Liz Vassey). He also appeared in such films as King of New York (1991), Boyz n the Hood (1991), and Man of Steel (2013).
- Main article: Michelle Forbes
Michelle Forbes (born 8 January 1965; age 56) was originally planned to reprise her role as Ro Laren in the series, turning the character into a regular (possibly the first officer of Deep Space 9). Forbes turned down the offer, and the character became the basis for Major Kira Nerys. (Captains' Logs: The Unauthorized Complete Trek Voyages)
As Forbes explained: "It was, again, about wanting variety in my career. If I'd gone on to do DS9, I might not have had the variety I've been lucky to have in my career. That's not to say I wasn't grateful for the opportunity; I genuinely was. However, I had to make a choice that felt right for me, which was a difficult one, especially as a young actor being offered a steady job." (TV Zone Magazine, January 2005)
- Main article: John Fleck
John Fleck (born 7 May 1951; age 69) was considered and auditioned for the role of Odo.  Fleck had previously appeared as Taibak in TNG: "The Mind's Eye". He later went on to play a Cardassian overseer in DS9: "The Homecoming", Ornithar in DS9: "The Search, Part I", Koval in DS9: "Inter Arma Enim Silent Leges", Abaddon in VOY: "Alice", and finally landed in the recurring role of Silik in Star Trek: Enterprise.
- Main article: Meg Foster
- Main article: Robert Foxworth
Robert Foxworth (born 1 November 1941; age 79) auditioned for a guest role in "Hippocratic Oath" (most likely as Goran'Agar). He would be cast later in the season as Admiral Leyton in the two-part "Homefront" and "Paradise Lost", as well as Vulcan administrator V'Las in the Star Trek: Enterprise season four episodes "The Forge", "Awakening" and "Kir'Shara". (Star Trek: Deep Space Nine Companion (p. ?))
- Main article: John Glover
- Main article: Whoopi Goldberg
Whoopi Goldberg (born 13 November 1955; age 65) was approached to do a cameo as Guinan in "Rivals" (where Martus Mazur would be revealed to be her wayward son), but had to turn it down as it conflicted with the filming of other projects (Goldberg also did not appear in any Next Generation episodes in the 1993-94 season). All references to Guinan were then removed from the episode's script. (Star Trek: Deep Space Nine Companion (p. ?))
- Main article: Barry Gordon
Barry Gordon (born 21 December 1948; age 72) was considered and auditioned for the role of Quark.  Gordon later appeared as two Ferengi characters: Nava in "The Nagus" and Ardon Broht in VOY: "Author, Author".
Robert Goulet (26 November 1933 – 30 October 2007; age 73) was a Canadian singer and actor, who was approached to play Vic Fontaine after Frank Sinatra, Jr. turned down the role. He also passed on the offer. (Star Trek: Deep Space Nine Companion (p. ?))
Goulet played a variety roles in film and television, including the TV-movie version of the musicals Brigadoon (1966), Carousel (1967), and Kiss Me Kate (1968), and appearances on such series as Mission: Impossible, Fantasy Island (starring Ricardo Montalban), The Love Boat, and Murder, She Wrote (starring William Windom). He also appeared in movies like Beetle Juice (1988, with Winona Ryder) and The Naked Gun 2 ½: The Smell of Fear (1991, with Peter Mark Richman, Tim O'Connor, and John Fleck). Goulet provided his singing voice for the animated film Toy Story 2 (2000), which also featured the voices of Wallace Shawn and Kelsey Grammer.
- See: Gary Graham
Grant is an American actress best known for her role as Julie Parrish in the 1983 science fiction miniseries V and its follow-ups, V: The Final Battle (1984) and V: The Series (1984-85). Grant was married to Star Trek: The Motion Picture actor Stephen Collins between 1985 and 2015.
- Main article: Bruce Greenwood
Bruce Greenwood (born 12 August 1956; age 64) was considered and auditioned for the role of Benjamin Sisko.  Greenwood later went on to play Captain Christopher Pike in Star Trek and Star Trek Into Darkness.
- Main article: Max Grodénchik
Max Grodénchik (born 12 November 1952; age 68) was considered and auditioned for the role of Quark.  Grodénchik was eventually cast in the recurring role of Quark's brother, Rom. He had previously appeared as Sovak in TNG: "Captain's Holiday" and Par Lenor in TNG: "The Perfect Mate".
- Main article: Ronald Guttman
- Main article: Martha Hackett
Martha Hackett (born 21 February 1961; age 59) auditioned for the role of Jadzia Dax, but lost out to Terry Farrell. ("Behind the Masks" panel at Destination Star Trek Birmingham, 21 October 2018) She was subsequently cast as the Terrellian pilot Androna in the final Star Trek: The Next Generation episode "All Good Things...", only to have her scene cut from the episode. Nevertheless, she was cast on Star Trek: Deep Space Nine, months later as the Romulan T'Rul in "The Search, Part I" and "The Search, Part II". Soon after, she was approached for yet another role, this time on Star Trek: Voyager, in the role of the treacherous Seska.
- Main article: Molly Hagan
Molly Hagan (born 3 August 1961; age 59) was considered for the role of Jadzia Dax, however she was unavailable at the time due to co-starring in the sitcom Herman's Head.  Hagan later appeared as Eris in "The Jem'Hadar".
Five years later, he had been cast to play Liam Bilby in the Star Trek: Deep Space Nine episode "Honor Among Thieves". He and actor Nick Tate were both up for the role, but director Allan Eastman (who had suggested Tate for the role) and producer Ira Steven Behr (who suggested Hallahan) chose Hallahan due to his resemblance to Miles O'Brien actor Colm Meaney, which they believed would give the characters a father-son quality to them. Sadly, Hallahan died of a heart attack before production began, and Tate assumed the role in Hallahan's memory. (Star Trek: Deep Space Nine Companion (p. ?); Find a Grave entry)
Hallahan is best known for his role in John Carpenter's The Thing. His other film credits include Silkwood (1983), Pale Rider (1985), Fatal Beauty (1987, starring Whoopi Goldberg and Harris Yulin), True Believer (1989), Dave (1993, with Frank Langella, Parley Baer, Stefan Gierasch, Stephen Root, Dawn Arnemann, Dendrie Taylor, Paul Collins, Peter White, Robin Gammell, Dan Butler, Tory Christopher, and Pam Pruitt-McGeary), Stuart Baird's Executive Decision (1996), and Dante's Peak (1997). He also made guest appearances on shows like Hawaii Five-O, M*A*S*H, Hill Street Blues, Law & Order, Murder, She Wrote, and NYPD Blue and had recurring roles on Hunter, The Paper Chase, and Grace Under Fire.
- Main article: Jerry Hardin
Jerry Hardin (born 20 November 1929; age 91) was considered and auditioned for the role of Odo.  Hardin had previously appeared as Radue in TNG: "When The Bough Breaks" and as Samuel Clemens in TNG: "Time's Arrow" and "Time's Arrow, Part II". He later appeared as Neria in VOY: "Emanations".
Hargitay is an Emmy and Golden Globe Award winning actress, best known for playing Detective Olivia Benson on the NBC drama series Law & Order: Special Victims Unit since 1999.
Hart is an American actress, best known for the original 1986 Highlander film, which co-starred Clancy Brown, and her role as Nurse Camille Shutt in the medical drama series Chicago Hope (1994-98), which co-starred Jayne Brook.
- Main article: Teri Hatcher
Teri Hatcher (born 8 December 1964; age 56) was considered for the role of Jadzia Dax, however she turned the offer down.  Hatcher had previously appeared as B.G. Robinson in TNG: "The Outrageous Okona".
- Main article: Jennifer Hetrick
Jennifer Hetrick (born 12 May 1958; age 62) was considered and auditioned for the role of Kira Nerys.  Hetrick had previously played Vash in TNG: "Captain's Holiday" and TNG: "Qpid", and went on to reprise the role in "Q-Less".
- Main article: Leslie Hope
Jana Marie Hupp
- Main article: Jana Marie Hupp
Jana Marie Hupp (born 2 April 1964; age 56) was considered and auditioned for the role of Jadzia Dax.  Hupp had previously played Ensign Pavlik in TNG: "Galaxy's Child" and Lieutenant Monroe in TNG: "Disaster".
- Main article: Famke Janssen
Famke Janssen (born 5 November 1965; age 55) is believed to have been offered the role of Jadzia Dax but she turned it down, wanting to focus on a film career rather than television. She had previously played Kamala in the Star Trek: The Next Generation episode "The Perfect Mate". The role of Jadzia Dax eventually went to Terry Farrell. Interestingly the forehead ridges seen on Trill in "The Host" were discarded in favor of spots similar ones seen on Kamala. (Star Trek: Deep Space Nine Companion (p. ?))
- Main article: Salome Jens
Salome Jens (born 8 May 1935; age 85) was considered for the role of Kai Opaka.  Jens later appeared as an Ancient humanoid in TNG: "The Chase", and was eventually cast in the recurring role of the Female Changeling from Star Trek: Deep Space Nine's third season onwards.
James Earl Jones
James Earl Jones (born 17 January 1931; age 90) was among the final few actors considered for the role of Benjamin Sisko, but eventually the role went to Avery Brooks. (Star Trek: Deep Space Nine Companion (p. ?))
During a career which spans more than fifty years, Jones appeared in numerous film and television projects. He is probably most famous for voicing the character of Darth Vader (played by David Prowse) in the original Star Wars trilogy and subsequent films and video games – a role which in the radio dramatizations of the films was handled by Brock Peters, who, in fact, played Sisko's father during DS9's run. He also lent his voice to the acclaimed animated feature The Lion King (1994), which also featured the voices of Whoopi Goldberg, Madge Sinclair, Frank Welker, and Brian Tochi. In live-action, Jones played the first African-American president in The Man (1972), which was directed by Joseph Sargent and also featured William Windom, Barry Russo, Garry Walberg, Vince Howard, and music by Jerry Goldsmith. His other feature film credits include Swashbuckler (1976, with Sid Haig and directed by James Goldstone), Exorcist II: The Heretic (1977, with Louise Fletcher), Coming to America (1988, with Madge Sinclair), Three Fugitives (1989, with Alan Ruck, Bruce McGill, and Brian Thompson), The Hunt for Red October (1990, with Gates McFadden and Daniel Davis), Patriot Games (1992, with music by James Horner) and Sommersby (1993, with William Windom). His television credits include guest roles in series such as L.A. Law (starring Corbin Bernsen), Stargate SG-1, and Homicide: Life on the Streets (starring Michelle Forbes). He also appeared in miniseries such as Jesus of Nazareth (1977, with Christopher Plummer) and Roots: The Next Generations (with Percy Rodrigues, Jason Wingreen, Brock Peters, Paul Winfield, Logan Ramsey, Bill Quinn, Patricia Smith, music by Gerald Fried, and partially directed by John Erman).
Jones is an accomplished stage actress and singer, whose Broadway credits include the musical Grind, for which she won a Tony Award as Best Featured Actress in a Musical. She is also a voice actress, whose credits include such the popular Monkey Island computer game series.
- Main article: Renée Jones
- Main article: Andreas Katsulas
Andreas Katsulas (18 May 1946 – 13 February 2006; age 59) was considered and auditioned for the role of Odo.  Katsulas had previously appeared as Commander Tomalak in TNG: "The Defector" and "Future Imperfect", and later reprised the role in "All Good Things...". He later also appeared as Drennik in ENT: "Cogenitor".
- Main article: Jack Kehler
- Main article: Clyde Kusatsu
Eriq La Salle
- See: Eriq La Salle
- Main article: Ed Lauter
Ed Lauter (30 October 1938 – 16 October 2013; age 74) was considered and auditioned for the role of Benjamin Sisko.  Lauter had previously appeared as Lieutenant commander Albert in TNG: "The First Duty".
German-born Lee is most famous for portraying Laura Palmer in the television series Twin Peaks (1990-91) and its subsequent movie spin-off, Twin Peaks: Fire Walk with Me (1992). She later appeared in films such as Backbeat (1994), Mother Night (1997) and series such as One Tree Hill and Desperate Housewives (starring Teri Hatcher).
Levine is most famous for portraying the serial killer "Buffalo Bill" in the 1991 film The Silence of the Lambs (which also featured Charles Napier), and Captain Leland Stottlemeyer in the television series Monk (in which Stanley Kamel had a recurring role) from 2002 to 2009. He also appeared in 1998 TV movie adaptation of Moby Dick, which starred Patrick Stewart as Captain Ahab and in films such as Flubber (1998, with Christopher McDonald, Wil Wheaton and Clancy Brown), Wild Wild West (1999), Ali (2001, with LeVar Burton), American Gangster (2007), and Shutter Island (2010).
- Main article: Kamala Lopez-Dawson
- Main article: Charles Lucia
Charles Lucia (born 3 January 1946; age 75) was considered and auditioned for the role of Benjamin Sisko.  Lucia had previously appeared as Ves Alkar in TNG: "Man of the People", and later went on to play Mabus in VOY: "Alliances", and Keene in ENT: "Fortunate Son".
- Main article: Franc Luz
- See: Stephen Macht
- Main article: Chase Masterson
Chase Masterson (born 26 February 1963; age 57) auditioned for the role of Mardah, Bajoran Dabo girl and girlfriend to Jake Sisko in "The Abandoned". Actor Avery Brooks, who was directing the episode, did not find their age difference between her and Cirroc Lofton plausible as a love interest for Jake.(Star Trek: Deep Space Nine Companion (p. 238)) Nevertheless, producers liked Masterson's playful performance enough that they would later bring back as another Bajoran dabo girl and love interest, Leeta, who, unlike the single-appearance Mardah, would recur in seventeen episode over five seasons.
- Main article: Jeff McCarthy
Jeff McCarthy was considered and auditioned for the role of Benjamin Sisko.  McCarthy had previously appeared as Roga Danar in TNG: "The Hunted", and went on to play the ill-fated Chief Medical Officer in VOY: "Caretaker".
- See: Roddy McDowall
- Main article: Malcolm McDowell
Malcolm McDowell (born 13 June 1943; age 77) wanted to play a role on Deep Space Nine. He only wanted to appear in an episode directed by his nephew, Alexander Siddig, and after his appearance as Doctor Tolian Soran in Star Trek Generations, he would have needed to play an alien, which he did not want to do. (citation needed • edit)
- Main article: Bruce McGill
Bruce McGill (born 11 July 1950; age 70) was considered for the role of Odo, however, he was not available due to filming a project titled Smouldering Lust at the time.  Later, McGill appeared as Captain Braxton in VOY: "Relativity".
- Main article: Stephen McHattie
Stephen McHattie (born 3 February 1947; age 73) was considered and auditioned for the role of Odo.  McHattie later appeared as Senator Vreenak in "In the Pale Moonlight", and as an Alien foreman in ENT: "The Xindi".
- Main article: Kate McNeil
Kate McNeil (born 17 August 1959; age 61) was considered for the role of Jadzia Dax, however, she was unavailable at the time due to co-starring in the series Bodies of Evidence. McNeil later appeared as Commander Collins in ENT: "Affliction".
- See: Eric Menyuk
- Main article: Tracy Middendorf
Tracy Middendorf (born 26 January 1970; age 50) also auditioned for the role of Mardah in "The Abandoned" (Cinefantastique, vol. 28, no. 4/5, p. 63) though Jill Sayre ultimately won the role. Middendorf would later become the second of three actresses to play Tora Ziyal, appearing once in "For the Cause".
- Main article: Katherine Moffat
Katherine Moffat (born 8 July 1958; age 62) was considered and auditioned for the role of Jadzia Dax.  Moffat had previously appeared as Etana in TNG: "The Game", and later went on to play Vaatrik Pallra in DS9: "Necessary Evil".
Moriarty is an Academy Award-nominated actress, best known for starring in the 1980 film Raging Bull, and also appearing in such films as Neighbors (1981), Kindergarten Cop (1990, featuring Jayne Brook), The Mambo Kings (1992), Matinee (1993, featuring Robert Picardo, William Schallert and Dick Miller), Casper (1995), and Analyze That (2002). She also appeared in such series as Tales from the Crypt and Law & Order.
- Main article: Phil Morris
Phil Morris (born 4 April 1959; age 61) was considered and auditioned for the role of Benjamin Sisko.  Morris had previously appeared as an Only boy in TOS: "Miri", and Cadet Foster in Star Trek III: The Search for Spock, and later went on to play Commander Thopok in DS9: "Looking for par'Mach in All the Wrong Places", Remata'Klan in DS9: "Rocks and Shoals", and Lieutenant John Kelly in VOY: "One Small Step".
Tim Blake Nelson
Tim Blake Nelson (born 11 May 1964; age 56) is the American actor, writer and director who auditioned for the role of Quark. Nelson thought the role was a natural fit for him, asserting that he "basically [is] a Ferengi." The part went to Armin Shimerman, which Nelson claimed left him "heartbroken." He began finding steady film work years later with directors such as Joel and Ethan Coen who, according to Nelson, were looking for "Human Ferengis." As Nelson stated, his "Ferengi career came, it just came later." 
Nelson first achieved recognition for his role as Delmar in the Coen brothers' acclaimed 2000 comedy O Brother, Where Art Thou? He has since had supporting roles in such films Steven Spielberg's Minority Report (with Patrick Kilpatrick, Neal McDonough, and George D. Wallace), Holes (with Eric Pierpoint, Jeff Ricketts, and Rick Worthy), Syriana (with Alexander Siddig, Christopher Plummer, Robert Foxworth, and David Clennon), The Astronaut Farmer (starring Virginia Madsen), and 2008's The Incredible Hulk. He has also written and directed such films as 2001's The Grey Zone (based on his own play) and Leaves of Grass (for which he cast Josh Pais). In 2019, Nelson starred in Watchmen.
- Main article: Sandra Nelson
Sandra Nelson (born 29 December 1964; age 56) was considered and auditioned for the role of Jadzia Dax.  Nelson later appeared as Marayna in VOY: "Alter Ego" and as Tavana in DS9: "Soldiers of the Empire".
- Main article: Julia Nickson
Julia Nickson (born 11 September 1958; age 62) was considered for the role of Jadzia Dax, however she was unavailable at the time due to filming a project titled Genghis Kahn. Nickson has previously appeared as Ensign Lian T'Su in The Next Generation episode "The Arsenal of Freedom" and later went on to play Cassandra in the Deep Space Nine episode "Paradise".
- Main article: Natalia Nogulich
Natalia Nogulich (born 1 October 1950; age 70) was considered for the role of Kai Opaka.  Nogulich was later cast as Admiral Alynna Nechayev in several episodes of both Star Trek: The Next Generation and Star Trek: Deep Space Nine.
Michael Nunez, Jr.
- Main article: Tricia O'Neil
Tricia O'Neil (born 11 March 1945; age 75) was considered for the role of Kai Opaka.  O'Neil had previously played Captain Rachel Garrett in TNG: "Yesterday's Enterprise". She later appeared as Kurak in TNG: "Suspicions" and as Korinas in DS9: "Defiant".
- Main article: Terry O'Quinn
Terry O'Quinn (born 15 July 1952; age 68) was considered for the role of Benjamin Sisko, however, he was not interested in science fiction projects at the time.  Later, O'Quinn appeared as Admiral Erik Pressman in TNG: "The Pegasus".
- Main article: Ed O'Ross
- Main article: Eric Pierpoint
Eric Pierpoint (born 18 November 1950; age 70) was considered and auditioned for the role of Benjamin Sisko.  Pierpoint later appeared as Voval in TNG: "Liaisons", Captain Sanders in DS9: "For the Uniform", Kortar in VOY: "Barge of the Dead", Shiraht in ENT: "Rogue Planet", and Harris in ENT: "Affliction", "Divergence", "Demons", and "Terra Prime".
Jon Polito (29 December 1950 – 1 September 2016; age 65) was considered for the role of Quark, however, he turned the offer down.  (citation needed • edit) Polito was a prolific character actors in both films and television, often playing policemen, such as Detective Steve Corsetti in the acclaimed drama series Homicide: Life on the Street, which co-starred Michelle Forbes. He appeared in five films by the Coen brothers, including Miller's Crossing (1990) and The Big Lebowski (1998) (co-starring David Huddleston).
- Main article: Iggy Pop
Iggy Pop (born 21 April 1947; age 73) was approached to play Grady in "Past Tense, Part II", but he was unavailable due to a music tour in Spain. (Star Trek: Deep Space Nine Companion (p. 200)) Ira Steven Behr, a fan of his work, pushed Iggy Pop to be cast for a role in the series, which resulted in him getting to play Yelgrun in "The Magnificent Ferengi" three years later.
- Main article: James Read
- Main article: Richard Riehle
Richard Riehle (born 12 May 1948; age 72) was considered and auditioned for the role of Odo.  Riehle had previously appeared as Batai in TNG: "The Inner Light", and went on to play Seamus in VOY: "Fair Haven" and "Spirit Folk", and Doctor Jeremy Lucas in ENT: "Cold Station 12" and "The Augments".
- Main article: Charles Rocket
- Main article: Andrew Robinson
Andrew J. Robinson (born 14 February 1942; age 78) originally auditioned for the role of Odo, and was briefly considered for the role of Laas in "Chimera", before they ultimately decided on J.G. Hertzler for the part. The creative staff thought Robinson's voice was unmistakable, and fans of Garak were very protective of the character, and wouldn't allow Robinson to play another role. (Star Trek: Deep Space Nine Companion (p. ?))
- Main article: Stephen Root
- Main article: William Sadler
William Sadler (born 13 April 1950; age 70) was considered and auditioned for the role of Benjamin Sisko.  Sadler later went on to portray Section 31 operative Luther Sloan in "Inquisition", "Inter Arma Enim Silent Leges", and "Extreme Measures".
- Main article: Carolyn Seymour
Carolyn Seymour (born 6 November 1947; age 73) was considered for the role of Kai Opaka.  Seymour has previously appeared as Sub-commander Taris in TNG: "Contagion" and as Mirasta Yale in TNG: "First Contact". She was last cast as Commander Toreth in TNG: "Face of the Enemy" and as Mrs. Templeton in VOY: "Cathexis" and VOY: "Persistence of Vision".
Martin Sheen (born 3 August 1940; age 80) is the multiple award-winning American actor, who was originally considered for the role of Section 31 operative Luther Sloan in "Inquisition" and consequent episodes. Producers finally chose William Sadler for the part. As Ira Steven Behr explained, "We needed someone who had real power as an actor, who could keep you from jumping to a final conclusion about his character." (Star Trek: Deep Space Nine Companion (p. 553))
Since the early 1960s, Sheen has established himself as a successful actor in both film and television. One of his earliest credits is "Nightmare", a 1963 episode of The Outer Limits, directed by John Erman, written and produced by Joseph Stefano and featuring Willard Sage, Whit Bissell, David Frankham, Bernard Kates, John Anderson, and Vic Perrin as the Control Voice. Also, Fred B. Phillips provided make-ups for the series, while Robert Justman served as first assistant director. His other television credits include episodes of Mission: Impossible ("Live Bait", with Dick Dial and John Crawford), Hawaii Five-O (including "Time and Memories", with Diana Muldaur), The F.B.I. (including "A Second Life", directed by Ralph Senensky and featuring George Sawaya, "Condemned" with James B. Sikking and "The Dynasty" with Ian Wolfe), Medical Center (starring James Daly, including "A Duel with Doom", with Marj Dusay), Columbo, and Two and a Half Men. In 1998 Sheen starred in the television film, Babylon 5: The River of Souls, based on the popular science fiction series running concurrent with Deep Space Nine. This telefilm also featured Tracy Scoggins. Sheen's most famous television role is that of President Josiah Bartlet in the popular series The West Wing, which ran from 1999 to 2006.
In feature films, Sheen has appeared in numerous acclaimed projects, including Francis Ford Coppola's classic Vietnam drama Apocalypse Now (1979), The Final Countdown (1980), Gandhi (1982), The Dead Zone (1983, with Anthony Zerbe), Wall Street (1987, with Saul Rubinek), Gettysburg (1993, with W. Morgan Sheppard), Dilinger and Capone (1995, with F. Murray Abraham, Stephen Davies, Catherine Hicks, Jeffrey Combs, Clint Howard, and Bert Remsen), Catch Me If You Can (2002, with Thomas Kopache and Malachi Throne), and The Departed (2006, with Mark Rolston).
Sheen has also branched out into video games with his portrayal of the Illusive Man in Mass Effect 2 (2010) and Mass Effect 3 (2012), which also featured the voices of Jennifer Hale, Raphael Sbarge, Robin Sachs, Keith Szarabajka, Michael Dorn, Armin Shimerman and Dwight Schultz.
- Main article: Gregory Sierra
Frank Sinatra, Jr.
Frank Sinatra, Jr. (10 January 1944 – 16 March 2016; age 72) was an American singer, songwriter, conductor and occasional actor, the son of Frank Sinatra. He was originally approached to play Vic Fontaine during the fourth season, after he turned out to be a fan of the show. Despite finding the role interesting, Sinatra turned it down, saying he only wanted to play an alien character. Finally the role went to James Darren. (Star Trek: Deep Space Nine Companion (p. ?))
Sinatra is best known as a vocalist and composer, who worked as his father's musical director and conductor from 1988. He also performed successfully with his own acts, touring thirty countries as early as 1968. Alongside his musical career, he occasionally appeared in film and television, including A Man Called Adam (1966, directed by Leo Penn), Zebra Force (1976, featuring Charles Dierkop and Anthony Caruso) and episodes of The Dean Martin Comedy Hour, Mercus Welby M.D., and The Love Boat. He also voiced himself in two episodes of Seth MacFarlane's animated series, Family Guy.
- Main article: Kurtwood Smith
Interestingly enough, Smith later appeared in "Things Past" as the Cardassian Thrax, wearing prosthetic makeup and playing the predecessor of Odo as security chief of Terok Nor. Smith also played the Federation President in Star Trek VI: The Undiscovered Country (in which he shared scenes with Rene Auberjonois), and Annorax in VOY: "Year of Hell" and VOY: "Year of Hell, Part II".
Staab is a former beauty queen, model and actress, known for her roles in such series as Guiding Light, Wonder Years and The Young and the Restless. She also played The Invisible Girl in the 1994 Roger Corman version of The Fantastic Four.
- Main article: Brenda Strong
Timmins is a Canadian actress, best known for her roles in the soap operas Ryan's Hope and Another World. She also appeared in guest roles in such series as Walker, the Texas Ranger, Frasier (starring Kelsey Grammer), and Highlander: The Series.
- Main article: Hallie Todd
- Main article: Tony Todd
Besides appearing as Worf's brother Kurn in episodes of The Next Generation and Deep Space Nine, Todd played Sisko's son, Jake in "The Visitor". He also appeared later as a Hirogen in "Prey". He also provided his voice for a number of Star Trek video games.
- Main article: Liz Vassey
- Main article: John Vickery
John Vickery (born 4 November 1950; age 70) was considered and auditioned for the role of Benjamin Sisko.  Vickery had previously appeared as Andrus Hagan in TNG: "Night Terrors", and later went on to play Gul Rusot in DS9: "The Changing Face of Evil", "When It Rains...", and "Tacking Into the Wind", and Orak in ENT: "Judgment".
- Main article: Robert Walker
Robert Walker (15 April 1940 – 5 December 2019; age 79) was approached in 1997 by the producers for a role on the sixth season of Deep Space Nine. He turned down the offer, as he was "not interested in renewing his acting career." (AOL chat, 1997)
- Main article: Basil Wallace
- Main article: Gwynyth Walsh
Gwynyth Walsh (born 1955) was considered and auditioned for the role of Kira Nerys.  Walsh had previously played B'Etor in TNG: "Redemption" and TNG: "Redemption II". She went on to reprise the role in DS9: "Past Prologue", TNG: "Firstborn", and Star Trek Generations. Later, she also appeared as Chief Examiner Nimira in VOY: "Random Thoughts".
Walsh has appeared in films such as 3 Men and a Little Lady (1990) and Point Break (1991), and in television series such as T.J. Hooker (starring William Shatner, James Darren and Richard Herd), Melrose Place, Lois and Clark: The New Adventures of Superman (starring Teri Hatcher), ER, and Crossing Jordan.
- Main article: David Warner
David Warner (born 29 July 1941; age 79) was approached by the producers for the role of Akorem Laan in "Accession". According to Ira Steven Behr, Warner wanted to do the role, but his wife talked him out of it, as they were on a vacation. (Captains' Logs Supplemental - The Unauthorized Guide to the New Trek Voyages)
Previously Warner played three roles in Star Trek: St. John Talbot in Star Trek V: The Final Frontier, Chancellor Gorkon in Star Trek VI: The Undiscovered Country, and Gul Madred in TNG: "Chain of Command, Part I" and "Part II".
Carl Weathers (born 14 January 1948; age 73) was considered and auditioned for the role of Benjamin Sisko. (Science Fiction Television Series, 1990-2004: Histories, Casts and Credits for 58 Shows, p.266)
- Main article: Edward Wiley
Edward Wiley (11 July 1955 – 16 October 1995; age 40) was considered and auditioned for the role of Odo.  Wiley had previously appeared as Governor Vagh in TNG: "The Mind's Eye", and later played Gul Toran in DS9: "Profit and Loss".
- Main article: Barbara Williams
- Main article: Fred Williamson
- Main article: Ray Wise
Ray Wise (born 20 August 1947; age 73) was considered for the role of Benjamin Sisko, however, he was not available at the time.  Wise had previously played Liko in TNG: "Who Watches The Watchers", and later went on to play Arturis in VOY: "Hope and Fear".
- Main article: Tom Wright