This page contains information regarding Star Trek: Lower Decks, and thus may contain spoilers.
Some Orion females secreted a highly potent pheromone that accelerated the metabolisms of males of many species, raising adrenaline production to dangerous levels. It caused aggression and a form of delusion that made the males susceptible to suggestion. The pheromone caused headaches in Human females and disrupted the sleep cycle of Denobulan males; Vulcans, however, were immune. The pheromone's effects were cumulative; the longer one was exposed, the more pronounced the results. In 2154, Doctor Phlox of the Enterprise NX-01 theorized that the pheromone acted as a defense mechanism against competition. (ENT: "Bound") Not all Orion females chose to secrete these pheromones. (LD: "We'll Always Have Tom Paris")
Denobulan females emitted powerful pheromones during their mating season. Male Denobulans often became combative during this time, and mating could require medical supervision. (ENT: "Dear Doctor", "A Night in Sickbay", "Bounty")
In The Adventures of Captain Proton holoprogram, the character of Queen Arachnia had, in her possession, a small vial of her pheromones, which she could use to seduce and control others. Kathryn Janeway, as Arachnia in 2375, used these pheromones against the character of Lonzak. (VOY: "Bride of Chaotica!")