A plasma reactor was a type of power generator that could be fueled by deuterium.

In 2257, the crew of USS Discovery used the abundant deuterium on Essof IV to create a plasma reactor that produced the equivalent energy of twelve warp cores, enough to power the phase discriminators needed to trap the Red Angel. (DIS: "The Red Angel")

The Tamarian deep space cruiser utilized a plasma reactor. During a standoff with such a Tamarian vessel in 2368, Data reported a power surge in their plasma reactor, indicating they were about to fire on a USS Enterprise-D shuttlecraft. (TNG: "Darmok")

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